Selective weakening of population-coupled synaptic activity in vivo in a mouse model of amyloid-beta pathologyL Melgosa-Ecenarro, CI Radulescu, N Doostdar, J Airey, FA Chaloner, J Jackson et al.
Characterising processing conditions that artifactually bias human brain tissue transcriptomesM Yaqubi, M Thomas, J Talbot-Martin, A Mohammadnia, A Allot, J Jackson et al.
Multi-'omic characterisation of vulnerable synaptic components in Alzheimer's DiseaseT Georgiades, EA Chandra, B Allehyany, E Schneegans, TKD Cheung, J Jackson et al.
Increased Extra-Synaptic Localisation of the Presynaptic Protein, SV2A, in the Human Alzheimer's Disease BrainS Williams, S Siddiqi, S Liu, R Patel, L Melgosa-Ecenarro, C Radulescu, J Jackson et al.
Post-mortem evidence of pathogenic angiogenesis and abnormal vascular function in early Alzheimer's diseaseDJ Asby, RA Fisher, J Jackson, S Love, PM Matthews, JS Miners
Intracellular accumulation of amyloid-β is a marker of selective neuronal vulnerability in Alzheimer's diseaseA Caramello, N Fancy, C Tournerie, M Eklund, V Chau, E Adair, J Jackson et al.
Cell state-dependent allelic effects and contextual Mendelian randomization analysis for human brain phenotypesA Haglund, V Zuber, M Abouzeid, Y Yang, JH Ko, L Wiemann, J Jackson et al.
A synaptic-astrocytic proteomic signature associated with synaptopathy in Alzheimer's Disease [preprint]J Griffiths, E Schneegans, H Whitwell, Z Qiu, B Notman, D Cheung, J Jackson et al.
Integrative multi-omics reveal glial signatures associated with accelerated cognitive decline in Alzheimer's disease [preprint]E Schneegans, N Fancy, M Thomas, E Adair, N Willumsen, J Jackson et al.
A single nuclear transcriptomic characterisation of mechanisms responsible for impaired angiogenesis and blood-brain barrier function in Alzheimer's diseaseS Tsartsalis, H Sleven, N Fancy, F Wessely, AM Smith, N Willumsen, J Jackson et al.
Characterisation of premature cell senescence in Alzheimer's disease using single nuclear transcriptomicsNN Fancy, AM Smith, A Caramello, S Tsartsalis, K Davey, RCJ Muirhead, J Jackson et al.
Mass spectrometry imaging highlights dynamic patterns of lipid co-expression with Aβ plaques in mouse and human brainsHX Huang, P Inglese, J Tang, R Yagoubi, GDS Correia, J Jackson et al.
Glial and neuronal mechanisms contributing to differential risks in TREM2 R47H and R62H variants in Alzheimer's DiseaseNN Fancy, N Willumsen, S Tsartsalis, C Khozoie, A Mcgarry, R Muirhead, J Jackson et al.
Pinpointing the locus of GABAergic vulnerability in Alzheimer's diseaseL Melgosa-Ecenarro, N Doostdar, CI Radulescu, JS Jackson, SJ Barnes
Seminars in Cell & Developmental Biology 139, 35–54DOI
2020
In vivo imaging of injured cortical axons reveals a rapid onset form of Wallerian degenerationAJ Canty, JS Jackson, L Huang, A Trabalza, C Bass, G Little, M Tortora et al.
Differential aberrant structural synaptic plasticity in axons and dendrites ahead of their degeneration in tauopathy [preprint]JS Jackson, JD Johnson, S Meftah, TK Murray, Z Ahmed, M Fasiolo et al.
Imbalance in the response of pre- and post-synaptic components to amyloidopathyTL Stephen, F Tamagnini, J Piegsa, K Sung, J Harvey, A Oliver-Evans, J Jackson et al.
Absence of interleukin-1 receptor 1 increases excitatory and inhibitory scaffolding protein expression and microglial activation in the adult mouse hippocampusU Avdic, D Chugh, H Osman, K Chapman, J Jackson, CT Ekdahl
Laser-Mediated Microlesions in Mouse Neocortex to Investigate Neuronal Degeneration and RegenerationJ Jackson, AJ Canty, L Huang, V De Paola
Current Protocols in Neuroscience 73 (1), 2.24.1–2.24.17DOI
2013
In-vivo single neuron axotomy triggers axon regeneration to restore synaptic density in specific cortical circuitsAJ Canty, L Huang, JS Jackson, GE Little, G Knott, B Maco, V De Paola
Synaptic elimination and protection after minimal injury depend on cell type and their prelesion structural dynamics in the adult cerebral cortexAJ Canty, LM Teles-Grilo Ruivo, C Nesarajah, S Song, JS Jackson et al.
The Journal of Neuroscience 33 (25), 10374–10383DOI
2012
Altered synaptic properties during integration of adult-born hippocampal neurons following a seizure insultJ Jackson, D Chugh, P Nilsson, J Wood, K Carlström, O Lindvall et al.
Functional integration of new hippocampal neurons following insults to the adult brain is determined by characteristics of pathological environmentJC Wood, JS Jackson, K Jakubs, KZ Chapman, CT Ekdahl, Z Kokaia et al.
Homing of stem cells to sites of inflammatory brain injury after intracerebral and intravenous administration: a longitudinal imaging studyJS Jackson, JP Golding, C Chapon, WA Jones, KK Bhakoo
An in vivo multimodal imaging study using MRI and PET of stem cell transplantation after myocardial infarction in ratsC Chapon, JS Jackson, EO Aboagye, AH Herlihy, WA Jones, KK Bhakoo
In vivo multimodal imaging of stem cell transplantation in a rodent model of Parkinson's diseaseJ Jackson, C Chapon, W Jones, E Hirani, A Qassim, K Bhakoo
Journal of Neuroscience Methods 183 (2), 141–148DOI